Frank Wright

Principal Bioinformaticist
T: +44 (0)344 928 5428 (*)


  • BSc in Zoology, with Physics and Mathematics, University of Glasgow.
  • MSc in Operational Research, University of Sussex.
  • Teaching qualification in Mathematics and Computing, Moray House, Edinburgh.
  • PhD in Molecular Evolution, University of Edinburgh.
  • Joined BioSS in 1989, based at Dundee since 1998.
  • Software development: Design of TOPALi application for phylogenetic, positive selection, and recombination detection analyses.
  • Statistics methodology: Methods to analyse of multiple sequence alignments, particularly to detect evidence of recombination.


  • Application of statistical/evolutionary methods to molecular sequence data and genomics data.
  • Providing training in molecular phylogenetics.

Areas of Expertise:

  • Computational Molecular Biology.
  • Molecular Sequence Analysis.
  • Phylogenetics.
  • Genomic Sequence Analysis.
  • Systems Biology.


Technical / contract reports

Conference papers

  • Opik, M.; Moora, M.; Saks, U.; Wheatley, R.E.; Wright, F.; Daniell, T.J.; Zobel, M. (2008) Boreo-nemoral herb-rich forest – a new biodiversity hotspot for arbuscular mycorrhizal fungi., Joint Meeting: European Ecological Federation and the Ecological Societies of Germany, Austria and Switzerland EURECO-GFOE 2008, Leipzig, Germany, 15-19 September 2008.
  • Ghasemi, S.; Wright, F.; Torrance, L.; Izadpanah, K. (2005) Detection and classification of potyviruses causing mosaic disease of sugarcane in Iran using molecular approaches., Second Asian Conference on Plant Pathology, Singapore, 25-28 June 2005.
  • Milne, I.; Wright, F.; Rowe, G.; Marshall, D.F.; Husmeier, D. (2004) TOPALi – Software for detecting recombinants in DNA multiple alignments., Plant and Animal Genome Conference (PAG) XII Proceedings, San Diego, California, 10-12 January 2004.
  • Lazarova, S.S.; Brown, D.J.F.; Malloch, G.; Oliveira, C.M.G.; Vandekerkhove, T.M.; Fenton, B.; Wright, F.; Lamberti, F.; Barsi, L.; Neilson, R. (2004) Phylogenetic relationships of the endosymbiont bacteria of Xiphinema americanum-Group nematodes., European Society of Nematologists Meeting, Rome, 14-18 June 2004.
  • Oliveira, C.M.G.; Hobschen, J.; Brown, D.J.F.; Monteiro, A.R.; Ferraz, L.C.C.B.; Wright, F.; Neilson, R. (2003) Taxonomic relationships of selected Xiphinema and Xiphidorus nematode species from Brazil., 16th Symposium of the Nematological Society of Southern Africa, South Africa, 30 June – 4 July 2003.
  • Oliveira, C.M.G.; Hubschen, J.; Brown, D.J.F.; Monteiro, A.R.; Ferraz, C.C.B.; Wright, F.; Neilson, R. (2003) Taxonomic relationships of selected Xiphinema and Xiphidorus nematode species from Brazil based on morphometrics and 18S rDNA gene sequences., Proceedings of the 55th International Symposium on Crop Protection, Ghent, Belgium, 6 May 2003.
  • Husmeier, D.; Wright, F. (2000) Detection of recombination in phylogenetic data sets with hidden Markov models., Mathematical and Statistical Aspects of Molecular Biology, Newton Institute, Cambridge, 4-5 April 2000.
  • Husmeier, D.; Wright, F. (2000) Detecting recombination with hidden Markov models., International Conference on Intelligent Systems for Molecular Biology (ISMB), La Jolla, California, 20-23 August 2000.
  • Husmeier, D.; Wright, F. (2000) Detecting sporadic recombination in DNA alignments with hidden Markov models., Proceedings of the 15th German Conference on Bioinformatics, Heidelberg, Germany, 5-7 October 2000, pp19-26.

Conference posters / abstracts

  • Lazarova, S.S; Brown, D.J.F.; Oliveira, C.M.G.; Fenton, B.; MacKenzie, K.; Wright, F.; Malloch, G.; Neilson, R. (2016) Diversity of endosymbiont bacteria associated with Xiphinema americanum-group parasitic nematodes., Linking Belowground Biodiversity and Ecosystem Function in European Forests, 4th BioLink COST Action Meeting, Sofia, Bulgaria, 12-14 April 2016. Poster.
  • Milne, I.; Lindner, D.; Wright, F. (2007) TOPAi v2: Extended multiple sequence alignment analysis software using web services and cluster computing., ISMB 2007, Vienna, 21-25 July 2007 (Poster).
  • Milne, I.; Wright, F. (2004) A simple algorithm to automatically detect recombinants in DNA/RNA sequence alignments., ISMB/ECCB 2004. Glasgow, 31 July – 4 August 2004. (Poster).