Malcolm Macaulay

Research

• Studying patterns of genetic variation shown by elite barley cultivars and the use of this information to gain insights into the control of characters of economic, agronomic, and environmental importance.
• Characterisation of agronomically important genes.
• High throughput SNP genotyping using Illumina Infinium 50K assay and associated analysis.
• Supervision, training, and management associated with Genome Technology
• Support for Genotyping at The James Hutton Institute, including troubleshooting software, hardware, and technical issues.
• STEM partner

Past research

• Biochemical and molecular marker development and utilisation in barley.

Publications

The following Publications have not yet been migrated to the James Hutton Institute's Pure service and relate to the research outputs from the two legacy organisations: The Macaulay Land Use Research Institute and The Scottish Crop Research Institute.

Journals

• Ramsay, L.; Comadran, J.; Druka, A.; Marshall, D.F.; Thomas, W.T.B.; Macaulay, M.; MacKenzie, K.; Simpson, C.G.; Fuller, J.; Bonar, N.; Hayes, P.M.; Lundqvist, U.; Franckowiak, J.D.; Close, T.J.; Muehlbauer, G.; Waugh, R. (2011) INTERMEDIUM-C, a modifier of lateral spikelet fertility in barley, is an ortholog of the maize domestication gene TEOSINTE BRANCHED 1., Nature Genetics, 43, 169-172.
• Cockram, J.; White, J.; Zuluaga, D.L.; Smith, D.; Comadran, J.; Macaulay, M.; Luo, Z.W.; Kearsey, M.J.; Werner, P.; Harrap, D.; Tapsell, C.; Liu, H.; Hedley, P.E.; Stein, N.; Schulte, D.; Steuernagel, B.; Marshall, D.F.; Thomas, W.T.B.; Ramsay, L.; Mackay, I.; Balding, D.J.; Waugh, R.; O’Sullivan, D.M.; Booer, C.; Pike, S.; Hamilton, G.; Jellis, G.; Davies, N.; Ross, A.; Bury, P.; Habgood, R.; Klose, S.; Vequaud, D.; Christerson, T.; Brosnan, J.; Newton, A.; Russel, J.; Shaw, P.; Bayles, R.; Wang, M. (2010) Genome-wide association mapping to candidate polymorphism resolution in the unsequenced barley genome, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 107, pp. 21611-21616.
• Druka, A.; Franckowiak, J.D.; Lundqvist, U.; Bonar, N.; Alexander, J.; Guzy-Wrobelska, J.; Ramsay, L.; Druka, I.; Grant, I.; Macaulay, M.; Vendramin, V.; Shahinnia, F.; Radovic, S.; Houston, K.; Harrap, D.; Cardle, L.; Marshall, D.F.; Morgante, M.; Stein, N.; Waugh, R. (2010) Exploiting induced variation to dissect quantitative traits in barley., Biochemical Society Transactions, 38, 683-688.
• Rae, S.J.; Macaulay, M.; Ramsay, L.; Leigh, F.; Matthews, D.; O’Sullivan, D.M.; Donini, P.; Morris, P.C.; Powell, W.; Marshall, D.F.; Waugh, R.; Thomas, W.T.B. (2007) Molecular barley breeding., Euphytica, 158, 295-303.
• Ramsay, L.; Russell, J.R.; Macaulay, M.; Booth, A.; Thomas, W.T.B. (2004) Variation shown by molecular markers in barley: Genomic and genetic constraints., Aspects of Applied Biology, 72, 147-154.
• Macaulay, M.; Ramsay, L.; Powell, W.; Waugh, R. (2001) A representative, highly informative ‘genotyping set’ of barley SSRs., Theoretical and Applied Genetics, 102, 801-809.
• Ramsay, L.; Macaulay, M.; degli Ivanissevich, S.D.; MacLean, K.; Cardle, L.; Fuller, J.D.; Edwards, K.J.; Tuvesson, S.; Morgante, M.; Massari, A.; Maestri, E.; Marmiroli, N.; Sjakste, T.; Ganal, M.; Powell, W.; Waugh, R. (2000) A simple sequence repeat-based linkage map of barley., Genetics, 156, 1997-2005.
• Cardle, L.; Ramsay, L.; Milbourne, D.; Macaulay, M.; Marshall, D.F.; Waugh, R. (2000) Computational and experimental characterization of physically clustered simple sequence repeats in plants., Genetics, 156, 847-854.
• Ramsay, L.; Macaulay, M.; Cardle, L.; Morgante, M.; degli Ivanissevich, S.; Maestri, E.; Powell, W.; Waugh, R. (1999) Intimate association of microsatellite repeats with retrotransposons and other dispersed repetitive elements in barley., Plant Journal, 17, 415-425.
• Russell, J.R.; Fuller, J.D.; Macaulay, M.; Hatz, B.G.; Jahoor, A.; Powell, W.; Waugh, R. (1997) Direct comparison of levels of genetic variation among barley accessions detected by RFLPs, AFLPs, SSRs and RAPDs., Theoretical and Applied Genetics, 95, 714-722.
• Russell, J.R.; Fuller, J.D.; Young, G.; Thomas, W.T.B.; Taramino, G.; Macaulay, M.; Waugh, R.; Powell, W. (1997) Discriminating between barley genotypes and microsatellite markers., Genome, 40, 442-450.
• Pakniyat, H.; Handley, L.L.; Thomas, W.T.B.; Connolly, T.; Macaulay, M.; Caligari, P.D.S.; Forster, B.P. (1997) Comparison of shoot dry weight, Na+ content and delta C-13 values of ari-e and other semi-dwarf barley mutants under salt-stress., Euphytica, 94, 7-14.

Books / chapters

• Ellis, R.P.; Macaulay, M.; Hackett, C.A.; Forster, B.P. (1998) The genetic control of ear emergence time in barley, Hordeum vulgare L.: Linkage between Vrn1, Bmy1, Wsp3 and a quantitative trait for time of ear emergence on chromosome 4H., In: Naqvi, S.S.M. (ed.). New Genetical Approaches to Crop Improvement. Atomic Energy Research Centre, Tando Jam 70060, Pakistan, pp619-630.
• Thomas, W.T.B.; Russell, J.R.; Bonar, N.; Booth, A.; Fuller, J.D.; Lawrence, P.; Macaulay, M.; Ramsay, L.; Waugh, R.; Powell, W. (1997) Simple sequence repeats SSRs and QTL mapping in barley crosses.., In: H. Buerstmayer & P. Ruckenbauer (eds.). Application of Marker Aided Selection in Cereal Breeding Programs. Eucarpia Section Cereals Meeting. Tulln, Austria, 28-29.

Technical / contract reports

• Macaulay, M.; Russell, J.R.; Ramsay, L.; Marshall, D.F.; Powell, W.; Waugh, R.; Thomas, W.T.B. (2004) Lessons from barley recommended lists., Annual Report of the Scottish Crop Research Institute for 2003/2004, pp144-145.
• Ramsay, L.; Caldwell, K.; Russell, J.R.; Macaulay, M.; Thomas, W.T.B.; Powell, W.; Waugh, R. (2003) Linkage disequilibrium in barley., Annual Report of the Scottish Crop Research Institute for 2002/2003, p114.
• Cardle, L.; Macaulay, M.; Marshall, D.F.; Milbourne, D.; Ramsay, L.; Waugh, R. (2000) SSR frequency and occurrence in plant genomes., Annual Report of the Scottish Crop Research Institute for 1999/2000, pp108-110.
• Thomas, W.T.B.; Newton, A.C.; Wilson, A.; Booth, A.; Macaulay, M.; Keith, R. (2000) Development of recombinant chromosome substitution lines – a barley resource., Annual Report of the Scottish Crop Research Institute for 1999/2000, pp99-100.
• Macaulay, M.; Provan, J.; Russell, J.R.; Fuller, J.D.; Dewar, H.; Milbourne, D.; Meyer, R.; Collins, A.; White, G.; Powell, W.; Waugh, R. (1996) Isolation, characterisation and use of SSRs as genetic markers., Annual Report of the Scottish Crop Research Institute for 1995, pp54-55.

Conference papers

• Moragues, M.; Russell, J.R.; Ceccarelli, S.; Grando, S.; Baum, M.; Macaulay, M.; Booth, A.; Waugh, R.; Ramsay, L.; Comadran, J.; Close, T.J.; de Young, J.; Flavell, A.J. (2008) High throughput SNP-based marker analysis of landrace barley., 10th International Barley Genetics Symposium, Alexandria, Egypt, 5-10 April 2008.
• Macaulay, M.; Ramsay, L.; Russell, J.R.; Marshall, D.F.; Waugh, R. (2004) Molecular markers to analyse breeding progress in barley., Aspects of Applied Biology, 72, 139-146.
• Macaulay, M.; Ramsay, L.; Waugh, R.; Thomas, W.T.B. (2004) Genes for success – what can we learn from recommended list trials?., Barley Genetics IX, Proceedings of 9th International Barley Genetics Symposium, Brno, Czech Republic, 20-26 June 2004, pp1040-1046.
• Russell, J.R.; Ramsay, L.; Booth, A.; Macaulay, M.; Cardle, L.; Marshall, D.F.; Powell, W.; Waugh, R. (2004) Development of gene based molecular markers in barley., Barley Genetics IX, Proceedings of 9th International Barley Genetics Symposium, Brno, Czech Republic, 20-26 June 2004.
• Ramsay, L.; Macaulay, M.; Thomas, W.T.B.; Druka, A.; Marshall, D.F.; Waugh, R. (2004) The semi-dwarfing gene sdw1 in European spring barley., Barley Genetics IX, Proceedings of 9th International Barley Genetics Symposium, Brno, Czech Republic, 20-26 June 2004, 321-325.
• Ellis, R.P.; Ramsay, L.; McLean, K.; Macaulay, M.; Waugh, R.; Powell, W. (2000) A molecular dissection of the genetic effects of domestication in barley., Proceedings of the 8th International Barley Genetics Symposium, Barley Genetics VIII (III), Adelaide, 22-27 October 2000, pp58-60.
• Waugh, R.; Ramsay, L.; Macaulay, M.; McLean, K.; Thomas, W.T.B.; Ellis, R.P.; Swanston, J.S.; Russell, J.R.; Cardle, L.; Harrower, B.E.; Hedley, P.E.; Powell, W.; Machray, G.C. (1999) Identification and improvement of components of barley malting quality., Proceedings of the 9th Australian Barley Technical Symposium, Melbourne, 12-16 September 1999, pp98-112.
• Macaulay, M.; Stephenson, P.; Gale, M.; Waugh, R. (1998) Development and assessment of SSR-based markers for application in genetical studies in barley and wheat., BBSRC PAGA/GAIT Workshop, Edinburgh, April 1998.
• Russell, J.R.; Fuller, J.D.; Macaulay, M.; Hatz, B.G.; Jahoor, A.; Powell, W.; Waugh, R. (1996) Direct comparisons of levels of genetic variation among barley accessions detected by RFLPs, AFLPs, SSRs and RAPDs., VII International Barley Genetics Symposium, Saskatoon, Canada, 5 August 1996, pp295-297.
• Powell, W.; Baird, E.; Booth, A.; Lawrence, P.; Macaulay, M.; Bonar, N.; Young, G.; Thomas, W.T.B.; McNicol, J.W.; Waugh, R. (1996) Single locus and multi-locus molecular assays for barley breeding and research., VII International Barley Genetics Symposium, Saskatoon, Canada, 5 August 1996, pp174-181.

Conference posters / abstracts

• Looseley, M.E.; Newton, A.C.; Atkins, S.D.; Fitt, B.D.L.; Fraaije, B.A.; Thomas, W.T.B.; Keith, R.; Macaulay, M.; Lynott, J.; Harrap, D. (2011) Resistance to Rhynchosporium secalis in a cross between winter and spring barley., Fourth International Workshop on Barley Leaf Blights, West Park Centre, Dundee, 27-29 June 2011.
• Comadran, J.; Ramsay, L.; William, T.; Macaulay, M.; Marshall, D.F.; Shaw, P.; Cockram, J.; White, J.; Mackay, I.; Liu, Z.; Kearsey, M.J.; O’Sullivan, D.; Waugh, R. (2011) Genetic selection footprints in elite barley cultivars., Plant and Animal Genome XIX, San Diego, California, USA, 15-19 January 2011. (Poster)
• Macaulay, M.; Ramsay, L.; Waugh, R.; Thomas, W.T.B. (2005) Prospects for marker assisted selection for nitrogen accumulation characters., ECO-PB/SUSVAR Abstracts, Dtiebergen, The Netherlands, 17-19 January 2005.
• Ramsay, L.; Macaulay, M.; Thomas, W.T.B.; Druka, A.; Marshall, D.F.; Waugh, R. (2004) The semi-dwarfing gene sdw1 in European spring barley., Plant & Animal Genome XII, San Diego, 10-14 January 2004, 187.
• Macaulay, M.; Stevenson, P.; Gale, M.; Waugh, R. (1997) Development and evaluation of SSRs in wheat and barley., BBSRC PAGA Annual Conference, Warwick, April 1997.
• Macaulay, M.; Stevenson, P.; Gale, M.; Waugh, R. (1996) Isolation and characterisation of simple sequence repeats from wheat and barley., BBSRC PAGA Annual Conference. Warwick, May 1996 (Poster).