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Luke Ramsay

Staff picture: Luke Ramsay
Cell and Molecular Sciences
Cell and Molecular Sciences
Barley Geneticist
Luke.Ramsay@hutton.ac.uk
+44 (0)344 928 5428 (*)

The James Hutton Institute
Invergowrie
Dundee DD2 5DA
Scotland UK

 

Current research interests

My research interests are centred on the development of genetics tools and genomics resources for barley and their application to breeding.  This underpins an interest in association genetics for agronomically important traits that has involved the development of high-throughput SNP genotyping capabilities.  This work has fostered closer ties with industry in particular breeding companies with UK-based programmes.  Interactions on dissection of genetic control of economic traits and the development of pre-breeding material will form the basis of much future work as will the possibilities that an ability to influence distribution and frequency of recombination would bring to longer-term breeding goals.

Current research projects

  • BBSRC Response Mode ‘R-Evolve’ BB/V016938/1 2021-2025 (£657,162) (Co-I)
  • BBSRC Response Mode BB/R010315/1 ‘Skinning’ 2017-2022 (£585,468) (Co-I)
  • EU H2020 101000622 RADIANT ReAlising DynamIc vAlue NeTworks for underutilised crops  (Co-I)
  • BBSRC Response Mode BB/T002905/1‘Developing nutrient-enriched cereal grains with large embryos’ (Co-I)
  • FACCE-JPI DEFRA CH0213 ‘Barista’ 2019-2022 (£60,000) (C0-I).

Past research

My initial research was based around studies on the quantitative genetics of Brassica spp. (University of Birmingham and John Innes Centre).  However since coming to the Institute I have concentrated almost exclusively on barley and have been involved mainly in the development of molecular markers and their application to questions relating to the patterns of genetic and functional diversity in barley.

Bibliography

  • Arrieta, M.; Colas, I.; Macaulay, M.; Waugh, R.; Ramsay, L. (2020) A modular tray growth system for barley., In: Pradillo M. & Heckmann S. (eds). Plant Meiosis. Methods in Molecular Biology, Humana, New York, Volume 2061, pp367-379.
  • Darrier, B.; Arrieta, M.; Mittmann, S.U.; Sourdille, P.; Ramsay, L.; Waugh, R.; Colas, I. (2020) Following the formation of synaptonemal complex formation in wheat and barley by high-resolution microscopy., In: Pradillo M. & Heckmann S. (eds). Plant Meiosis. Methods in Molecular Biology, Humana, New York, Volume 2061, pp207-215.
  • Mittmann, S.; Arrieta, M.; Ramsay, L.; Waugh, R.; Colas, I. (2019) Preparation of barley pollen mother cells for confocal and super resolution microscopy., In: Harwood, W.A. (ed.). Barley: Methods and Protocols. Methods Molecular Biology, Volume 1900, Humana Press, New York. Chapter 11, pp167-179.
  • Ramsay, L.; Colas, I.; Waugh, R. (2014) Modulation of meiotic recombination., In: Kumlehn, J. & Stein, N. (eds.). Biotechnological Approaches to Barley Improvement, Part II. Springer, Berlin, Chapter 16, pp311-329.
  • Waugh, R.; Flavell, A.J.; Russell, J.R.; Thomas, W.T.B.; Ramsay, L.; Comadran, J. (2014) Exploiting barley genetic resources for Genome Wide Association Scans (GWAS)., Tuberosa, R., Graner, A. & Frison, E. (eds.). Genomics of Plant Genetic Resources. Volume 1. Managing, Sequencing and Mining Genetic Resources. Springer, The Netherlands, Chapter 10, pp237-254.
  • Powell, W.; Waugh, R.; Bradshaw, J.E.; Russell, J.R.; Ramsay, L. (2006) Introduction to classical genetics and plant breeding., In: Christou, P. & Klee, H. (eds.). Handbook of Plant Biotechnology. 2nd ed. John Wiley and Sons Ltd, Chichester, pp3-29.
  • Thomas, W.T.B.; Russell, J.R.; Bonar, N.; Booth, A.; Fuller, J.D.; Lawrence, P.; Macaulay, M.; Ramsay, L.; Waugh, R.; Powell, W. (1997) Simple sequence repeats SSRs and QTL mapping in barley crosses.., In: H. Buerstmayer & P. Ruckenbauer (eds.). Application of Marker Aided Selection in Cereal Breeding Programs. Eucarpia Section Cereals Meeting. Tulln, Austria, 28-29.

  • Thomas, W.T.B.; Comadran, J.; Ramsay, L.; Shaw, P.; Marshall, D.F.; Newton, A.C.; O'Sullivan, D.; Cockram, J.; Mackay, I.; Bayles, R.; White, J.; Kearsey, M.J.; Luo, Z.; Wang, M.; Tapsell, C.; Harrap, D.; Werner, P.; Klose, S.; Bury, P.; Wroth, J.; Argilllier, O.; Habgood, R.; Glew, M.; Bochard, A-M.; Gymer, P.; Vequaud, D.; Christerson, T.; Allvin, B,; Davies, N.; Broadbent, R.; Brosnan, J.; Bringhurst, T.; Booer, C.; Waugh, R. (2014) Association genetics of UK elite barley (AGOUEB)., Final Project Report to HGCA, No 528, 125pp.
  • Ramsay, L.; Thomas, W.T.B.; Comadran, J.; Marshall, D.F.; Shaw, P.; Waugh, R. (2011) Genetic diversity in modern barley varieties., Annual Report of the Scottish Crop Research Institute for 2010, pp23-24.
  • Ramsay, L.; Rostoks, N.; Marshall, D.F.; Mudie, S.; Close, T.J.; Waugh, R. (2006) Breeding facilitates whole genome LD-mapping., Annual Report of the Scottish Crop Research Institute for 2006, pp16-17.
  • Macaulay, M.; Russell, J.R.; Ramsay, L.; Marshall, D.F.; Powell, W.; Waugh, R.; Thomas, W.T.B. (2004) Lessons from barley recommended lists., Annual Report of the Scottish Crop Research Institute for 2003/2004, pp144-145.
  • Ramsay, L.; Caldwell, K.; Russell, J.R.; Macaulay, M.; Thomas, W.T.B.; Powell, W.; Waugh, R. (2003) Linkage disequilibrium in barley., Annual Report of the Scottish Crop Research Institute for 2002/2003, p114.
  • Thomas, W.T.B.; Waugh, R.; Ramsay, L.; Russell, J.R.; Powell, W.; Meyer, R.C.; Young, G.R.; Lawrence, P.E.; Booth, A.; Swanston, J.S.; Newton, A.C. (2002) Molecular markers for agriculturally important traits in barley., Annual Report of the Scottish Crop Research Institute for 2001/2002, 162-164.
  • Caldwell, D.; McCallum, N.; Mudie, S.; Hedley, P.E.; Ramsay, L.; Liu, H.; Marshall, D.F.; Waugh, R. (2002) A physical/chemical mutation grid for barley functional genomics., Annual Report of the Scottish Crop Research Institute for 2001/2002, pp157-158.
  • Ramsay, L.; Hedley, P.E.; Liu, H.; McCallum, N.; Mudie, S.; Cardle, L.; Harrower, B.E.; Machray, G.C.; Marshall, D.F.; Waugh, R. (2002) Barley transcriptome resources., Annual Report of the Scottish Crop Research Institute for 2001/2002, pp151-152.
  • Bryan, G.J.; Milbourne, D.; Isidore, E.; McNicoll, J.; Tierney, I.; Purvis, A.; Williamson, S.; Ramsay, L.; McLean, K.; Waugh, R. (2002) Application of a potato UHD genetic linkage map for BAC landing and contig initiation in a region of linkage group V., Annual Report of the Scottish Crop Research Institute for 2001/2002, pp143-146.
  • James, A.B.; Bryan, G.J.; Dear, PH.; Thangavelu, M.; Ramsay, L.; Waugh, R. (2001) High density, high throughput physical mapping in plants., Annual Report of the Scottish Crop Research Institute for 2000/2001, pp79-81.
  • Cardle, L.; Macaulay, M.; Marshall, D.F.; Milbourne, D.; Ramsay, L.; Waugh, R. (2000) SSR frequency and occurrence in plant genomes., Annual Report of the Scottish Crop Research Institute for 1999/2000, pp108-110.
  • Waugh, R.; Ramsay, L.; Graner, A.; Bauer, E.; Morgante, M.; Degli Ivanissevich, S.; Isaac, P.; Jahoor, A.; Herz, M.; Tuvesson, S.; Dourlein, J.; Chasalow, S.; Marmiroli, N.; Massari, A.; Rath, F.; Schacht, J.; Jaiser, H.; Schiemann, A.; Habgood, R.; Hemker, R.; Ferrer, E.G (1999) Improving the quality of European barley: application and development of appropriate enabling technologies., Final Confidential Report FAIR CT95-00031999, 23pp.
  • Ellis, R.P.; Russell, J.R.; Ramsay, L.; Waugh, R.; Powell, W. (1999) Barley domestication - Hordeum spontaneum, a source of new genes for crop improvement., Annual Report of the Scottish Crop Research Institute for 1998/99, 97-100.
  • Waugh, R.; Collins, A.; Milbourne, D.; Ramsay, L.; Meyer, R.C.; Hackett, C.A.; Bradshaw, J.E.; Gebhardt, C.; Bonnel, E.; Bonar, N. (1998) Development of markers for potato genetics and breeding., Annual Report of the Scottish Crop Research Institute for 1997/98, 86-88.
  • Waugh, R.; Ramsay, L. (1996) EU FAIR CT95-0003., Second Year Consolidated Report.

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The James Hutton Research Institute is the result of the merger in April 2011 of MLURI and SCRI. This merger formed a new powerhouse for research into food, land use, and climate change.