RenSeq is a cutting-edge genome reduction technology.

RenSeq, which stands for Resistance gene enrichment Sequencing, enables researchers and breeders to unravel the complex family of nucleotide-binding, leucine-rich-repeat genes (NLRs). These genes hold the key to controlling a wide range of potato pathogens, from late blight to viruses and nematodes amongst others.

RenSeq Technology enables us to:

  • Annotate Disease Resistance Genes: Explore and annotate disease resistance genes in genomes with precision.
  • Genetically Map New Resistances: Employ techniques like bulked-segregant analysis to map novel resistances effectively.
  • Identify Candidate Resistance Genes: Utilise long-read-based representation of disease resistance genes with SMRT-RenSeq.
  • Evaluate Functional Genes: Determine the presence or absence of functional disease resistance genes in wild species, cultivars, and breeding clones through dRenSeq. This knowledge enables the informed parental selection to combine effective resistance in breeding programs.
  • Create Accurate Markers: Develop highly-transferable and accurate markers to track functional resistances in breeding programs using mRenSeq.
  • Advance Association Genetics: Apply association genetics to explore elusive genes used in potato cultivars through SMRT-AgRenSeq-d.


RenSeq technology is an integral part of our research and commercial breeding activities, collaborating closely with James Hutton Limited and international partners.