J. William (Will) Allwood
For over 19 years Will has made major contributions in the field of metabolomics and metabolite profiling. He is interested in the study and development of chromatography - linked - mass spectrometry (LC and GC) for a range of applications in the fields of plant-physiology, pathology and insect interactions, as well as natural product discovery. Will was a core researcher within the two teams who were first recognised for applying metabolomics approaches to the study of plant disease and insect interactions. Will has previously run and provided metabolic profiling services within the Universities of Manchester and Birmingham across many plant science, microbiological and clinical, studies. Will is currently responsible for the LC-MS metabolomics services at James Hutton Institute – Dundee, where he serves as both an LC-MS technologist and a research scientist. Will also serves as the current deputy leader of the Plant Biochemistry and Food Quality (PBFQ) programme. Will collaborates within a large international network (e.g. Max Plank Institute for molecular plant physiology – Golm, Plant Research International - Wageningen University, and INRAe Bordeaux), he has a strong track record of producing high impact publication outputs (H index 29, i10 index 55 (09/12/21)). Dr Allwood currently serves as the chair of the Scottish Metabolomics Network as well as being a member of the Springer Metabolomics journal editorial board.
Measures of esteem:
- MDPI Metabolites (Section editor, Plant metabolomics: 2020-present)
- Springer Metabolomics journal (Editorial Board Member 2011-present)
- Springer Metabolomics journal (Guest editor for themed collection on Food and nutrition, 2017-2018)
- The Scottish Metabolomics Network (Board Member 2017-present)
- Local organiser for the International Metabolomics Society conference, Manchester 2007.
- Local organiser for The Metabolic Profiling Forum – MetaboMeeting, International Conference, Manchester 2012.
- Local organiser for The Scottish Metabolomics Network – annual meeting, Dundee, 1-2nd November 2018.
- Reviewer for the following SCI journals: Analytical Chemistry, Journal of Proteome Research, Journal of Natural Products, Rapid Communications in Mass Spectrometry, Analytical Biochemistry, Analyst, Analytical and Bioanalytical Chemistry, Journal of Chromatography A, Journal of Chromatography B, Metabolomics, Metabolites, Frontiers in metabolomics, Plant Physiology, Plant Cell, Plant Journal, Journal of Experimental Botany, Phytochemistry, Physiologia Plantarum, Journal of Agricultural and Food Chemistry, Phytochemical Analysis, Environmental and Experimental Botany, Plant Methods, Frontiers in plant biology.
Current research interests
- 2020-2023: Scottish Government. Endophyte grasses: assessing the risk to Scotland (EndoScot). Total value £117,457 (Co-I)
- 2020-2021: IN-U-Bar: Improving nitrogen utilisation in barley for the Scottish distilling and brewing industry. Hutton Seedcorn. Total Value £25K (Lead-I)
- 2016-2021. Scottish Government Strategic Research Programme, Theme 3 – Food, health and Wellbeing, WP 3.1 - Improving Food and Drink Production
- 2016-2020. H2020: GOODBERRY - Improving the Stability of High-Quality Traits of Berry in Different Environments and Cultivation Systems for the Benefit of European Farmers and Consumers. EU, £3.5M (Co-I)
- 2018-2019. Feasibility of developing a novel breeding methodology to improve berry flavour. Innovate UK, Co-I. £210.5K (Co-I)
- 2016-2018. Strategies to reduce waste due to greening in potato tubers. Innovate UK, £237K (Co-I)
Bibliography
- McDougall, G.J.; Allwood, J.W.; Austin, C.; Dobson, G.; Verrall, S.; Alexander, C.J.; Hancock, R.D.; Graham, J.; Hackett, C. (2023) Quantitative trait loci mapping of polyphenol metabolites from a ‘Latham’ x ‘Glen Moy’ red raspberry (Rubus idaeus L) cross, Metabolomics, 19(8), Art. 7
- Torrens, A.A.; Mitchell, C.A.; Pourshahidi, L.K.; Óg Murphy, B.; Allwood, J.W.; Rizzetto, L.; Scholz, M.; Tuohy, K.; Pereira-Caro, G.; Moreno_Rojas, J.M.; McDougall, G.; Gill, C.I.R. (2023) Long-term supplementation with anthocyanin-rich or -poor Rubus idaeus berries does not influence microvascular architecture nor cognitive outcome in the APP/PS-1 mouse model of Alzheimer’s disease, International Journal of Food Sciences and Nutrition, 74(1), 33-50
- McLoone, P.; Tabys, D.; Yunussova, S.; Zhumbayeva, A.; Sungurtas, J.; Verrall, S.; Austin, C.; Allwood, W.; McDougall, G. (2022) Qualitative phytochemical analysis and in vitro investigation of the immunomodulatory properties of honeys produced in Kazakhstan, Natural Product Research, 37(6), 996-1001
- Scolari, L. M.; Hancock, R.; Graham, J.; Freitag, S.; Verrall, S.; Moreno-Melada, A. R.; Allwood, W. (2022) Hormone profiling in artificially induced ‘crumbly’ fruit in raspberry (Rubus idaeus L.) at two different development stages, The Journal of Horticultural Science and Biotechnology, 98(3), 384-393
- Arnold , H.; Dobson, G.; Foito, A.; Austin, C.; Sungurtas, J.; Allwood, W.; Stewart, D.; McDougall, G. (2022) Assessing available phytochemicals from commercial blackcurrant and raspberry pomaces, Journal of Berry Research, 12, 415-431
- Huertas, R.; Allwood, J. W.; Hancock, R. D.; Stewart, D. (2022) Iron and zinc bioavailability in common bean (Phaseolus vulgaris) is dependent on chemical composition and cooking method, Food Chemistry, 387, Art. 132900
- Mcloone, P.; Zhumbayeva, A.; Yunussova, S.; Kaliyev, Y.; Yevstafeva, L.; Sungurtas, J.; Verrall, S.; Austin, C.; Allwood, W.; McDougall, G.J. (2021) Identifcation of components in Kazakhstan honeys that correlate with antimicrobial activity against wound and skin infecting microorganisms, BMC Complementary Medicine and Therapies, 21, Art. 300
- Allwood, W.; Martinez-Martin, P.; Xu, Y.; Cowan, A.; Pont, S.; Griffiths, I.; Sungurtas, J.; Clarke, S.; Goodacre, R.; Marshall, A.; Stewart, D.; Howarth, C. (2021) Assessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches, Food Chemistry, 335, Art. 12958
- Allwood, W.; Williams, A.; Uthe, H.; Van Dam, N.M. ; Mur, L.A.J. ; Grant, M.R. ; Pétriacq, P.; (2021) Unravelling Plant Responses to Stress—The Importance of Targeted and Untargeted Metabolomics, Metabolites, 11(8), Art. 558
- Alkhalefah, A.; Dunn, W. B.; Allwood, W.; Parry, K. L.; Houghton, F. D ; Ashton, N.; Glazier, J .D. (2021) Maternal intermittent fasting during pregnancy induces fetal growth restriction and down-regulated placental system A amino acid transport in the rat, Clin Sci (Lond), 135(11), 1445 - 1466
- Biancacci, C.; McDougall, G.J.; Allwood, J.W.; Day, J.G.; Davidson, K.; Stanley, M.S. (2021) LC-MSn profiling reveals seasonal variation in the composition of Osmundea pinnatifida (Hudson) Stackhouse, Journal of Applied Phycology, 33, 2443-2458
- Lima, R.C.L.; Böcker, U.; McDougall, G.J.; Allwood, J.W.; Afseth, N.K.; Wubshet, S.G. (2021) Magnetic ligand fishing using immobolized DPP-IV for identification of antidiabetic ligands in lingonberry extract, PLoS ONE, 16(2), Article No. e0247329
- Dobani, S.; Latimer, C.; McDougall, G.J.; Allwood, J.W.; Pereira-Caro, G.; Moreno-Rojas, J.M.; Ternan, N.G.; Pourshahidi, L.K.; Lawther, R.; Tuohy, K.M.; Del Rio; D.; O’Connor, G.; Rowland, I.; Almutairi, M.T.; Crozier, A.; Gill, C.I.R. (2021) Ex vivo fecal fermentation of human ileal fluid collected after raspberry consumption modifies (poly)phenolics and modulates genoprotective effects in colonic epithelial cells., Redox Biology, 40, Article No. 101862
- Allwood, J.M.; Gibon, Y.; Osorio, S.; Araújo, W.L.; Vallarino, J.G.; Pétriacq, P.; Moing, A. (2021) Developmental metabolomics to decipher and improve fleshy fruit quality., Advances in Botanical Research, 98, 3-34
- Abukhabta, S,; Ghawi, S.K.; Karatzas, K.A.; Charalampopoulos, D.; McDougall, G.; Allwood, J.W.; Verrall, S.; Lavery, S.; Latimer, C.; Pourshahidi, K.; Lawther, R.; O’Connor, G.; Rowland, I.; Gil, C.I.R. (2021) Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforphane., European Journal of Nutrition, 60, 1263-1276
- Matos, M.S.; Anastácio, J.D.; Allwood, J.W.; Carregosa, D.; Marques, D.; Sungurtas, J.; McDougall, G.J.; Menezes, R.; Matias, A.A.; Stewart, D.; Nunes dos Santos, C. (2020) Assessing the intestinal permeability and anti-inflammatory potential of sesquiterpene lactones from chicory., Nutrients, 12, Article No. 3547.
- Allwood, J.W.; Evans, H.; Austin, C.; McDougall, G.J. (2020) Extraction, Enrichment, and LC-MSn-Based Characterization of Phlorotannins and Related Phenolics from the Brown Seaweed, Ascophyllum nodosum, Marine Drugs, 18, Article No. 448.
- Okamoto, H.; Ducreux, L.J.M.; Allwood, J.W.; Hedley, P.E.; Wright, A.; Gururajan, V.; Terry, M.J.; Taylor, M.A. (2020) Light regulation of chlorophyll and glycoalkaloid biosynthesis during tuber greening of potato S. tuberosum., Frontiers in Plant Science, 11, Article No. 753.
- Moing, A.; Allwood, J.W.; Aharoni, A.; Baker, J.; Beale, M.H.; Ben-Dor, S.; Biais, B.; Brigante, F.; Burger, Y.; Deborde, C.; Erban, A.; Faigenboim, A.; Gur, A.; Goodacre, R.; Hansen, T.H.; Jacob, D.; Katzir, N.; Kopka, J.; Lewinsohn, E.; Maucourt, M.; Meir, S.; Miller, S.; Mumm, R.; Oren, E.; Paris, H.S.; Rogachev, I.; Rolin, D.; Saar, U.; Schjoerring, J.K.; Tadmor, Y.; Tzuri, G.; de Vos, R.C.H.; Ward, J.L.; Yeselson, E.; Hall, R.D.; Schaffer, A.A. (2020) Comparative metabolomics and molecular phylogenetics of melon (Cucumis melo, Cucurbitaceae) biodiversity., Metabolites, 10, Article No.121.
- McDougall, G.J.; Foito, A.; Dobson, G.; Austin, C.; Sungartas, J.; Su, S.; Wang, L.; Feng, C.; Li, S.; Wang, L.; Wei, W.; Allwood, J.W.; Stewart, D. (2020) Glutathionyl-S-chlorogenic acid is present in fruit of Vaccinium species, potato tubers and apple juice., Food Chemistry, 330, Article No. 127227.
- Mori, K.; Beauvoit, B.P.; Benoît, B.; Maxime, C.; Allwood, J.W.; Deborde, C.; Maucourt, M.; Goodacre, R.; Cabasson, C.; Moing, A.; Rolin, D.; Gibon, Y. (2019) Central metabolism Is tuned to the availability of oxygen in developing melon fruit., Frontiers in Plant Science, 10, Article No.594.
- Hayward, N.J.; McDougall, G.J.; Farag, S.; Allwood, J.W.; Austin, C.; Campbell, F.; Horgan, G.; Ranawana, V. (2019) Cinnamon shows antidiabetic properties that are species-specific: effects on enzyme activity inhibition and starch digestion., Plant Foods for Human Nutrition, 74, 544-552.
- Haugeneder, A.; Trinkl, J.; Hartl, K.; Hoffmann, T.; Allwood, J.W.; Schwab, W. (2019) Correction to: answering biological questions by analysis of the strawberry metabolome (vol 14, 145, 2018)., Metabolomics, 15, p40.
- Kallscheuer, N.; Menezes, R.; Foito, A.; Silva, M.H.; Braga, A.; Dekker, W.; Sevillano, D.M.; Rosado-Ramos, R.; Jardim, C.; Oliveira, J.; Ferreira, P.; Rocha, I.; Silva, A.R.; Sousa, M.; Allwood, J.W.; Bott, M.; Faria, N.; Stewart, D.; Ottens, M.; Naesby, M.; Santos, C.N.; Marienhagen, J. (2019) Identification and microbial production of the raspberry phenol Salidroside that is active against Huntington’s Disease., Plant Physiology, 179, 969-985.
- Allwood, J.W.; Xu, Y.; Martinez-Martin, P.; Palau, R.; Cowan, A.; Goodacre, R.; Marshall, A.; Stewart, D.; Howarth, C. (2019) Rapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats., Metabolomics, 15, Article No. 42.
- Allwood, J.W.; Woznicki, T.L.; Xu, Y.; Foito, A.; Aaby, K.; Sungurtas, J.; Freitag, S.; Goodacre, R.; Stewart, D.; Rember, S.F.; Heide, O.M.; Sønsteby, A. (2019) Application of HPLC-PDA-MS metabolite profiling to investigate the effect of growth temperature and day length on blackcurrant fruit., Metabolomics, 15, Article No. 12.
- Solopova, A.; van Tilburg, A.Y.; Foito, A.; Allwood, J.W.; Stewart, D.; Kulakauskas, S.; Kuipers, O.P. (2019) Engineering Lactococcus lactis for the production of unusual anthocyanins using tea as substrate., Metabolic Engineering, 54, 160-169.
- Logie, L.; Lees, Z.; Allwood, J.W.; McDougall, G.J.; Beall, C.; Rena, G. (2018) Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)., Diabetes, Obesity and Metabolism, 20, 2748-2758.
- Freitag, S.; Verrall, S.R.; Pont, S.D.A.; McRae, D.; Sungartas, J.A.; Palau, R.; Hawes, C.; Alexander, C.J.; Allwood, J.W.; Foito, A.; Stewart, D.; Shepherd, L.V.T. (2018) Impact of conventional and integrated management systems on the water-soluble vitamin content in potatoes, field beans and cereals., Journal of Agricultural and Food Chemistry, 66, 831-841.
- Austin, C.; Stewart, D.; Allwood, J.W.; McDougall, G.J. (2018) Extracts from the edible seaweed, Ascophyllum nodosum, inhibit lipase activity in vitro: contributions of phenolic and polysaccharide components., Food and Function, 9, 502-510.
- McDougall, G.J.; Allwood, J.W.; Austin, C.; Dobson, G.; Verrall, S.; Alexander, C.J.; Hancock, R.D.; Graham, J.; Hackett, C. (2023) Quantitative trait loci mapping of polyphenol metabolites from a ‘Latham’ x ‘Glen Moy’ red raspberry (Rubus idaeus L) cross, Metabolomics, 19(8), Art. 7
- Torrens, A.A.; Mitchell, C.A.; Pourshahidi, L.K.; Óg Murphy, B.; Allwood, J.W.; Rizzetto, L.; Scholz, M.; Tuohy, K.; Pereira-Caro, G.; Moreno_Rojas, J.M.; McDougall, G.; Gill, C.I.R. (2023) Long-term supplementation with anthocyanin-rich or -poor Rubus idaeus berries does not influence microvascular architecture nor cognitive outcome in the APP/PS-1 mouse model of Alzheimer’s disease, International Journal of Food Sciences and Nutrition, 74(1), 33-50
- McLoone, P.; Tabys, D.; Yunussova, S.; Zhumbayeva, A.; Sungurtas, J.; Verrall, S.; Austin, C.; Allwood, W.; McDougall, G. (2022) Qualitative phytochemical analysis and in vitro investigation of the immunomodulatory properties of honeys produced in Kazakhstan, Natural Product Research, 37(6), 996-1001
- Scolari, L. M.; Hancock, R.; Graham, J.; Freitag, S.; Verrall, S.; Moreno-Melada, A. R.; Allwood, W. (2022) Hormone profiling in artificially induced ‘crumbly’ fruit in raspberry (Rubus idaeus L.) at two different development stages, The Journal of Horticultural Science and Biotechnology, 98(3), 384-393
- Arnold , H.; Dobson, G.; Foito, A.; Austin, C.; Sungurtas, J.; Allwood, W.; Stewart, D.; McDougall, G. (2022) Assessing available phytochemicals from commercial blackcurrant and raspberry pomaces, Journal of Berry Research, 12, 415-431
- Huertas, R.; Allwood, J. W.; Hancock, R. D.; Stewart, D. (2022) Iron and zinc bioavailability in common bean (Phaseolus vulgaris) is dependent on chemical composition and cooking method, Food Chemistry, 387, Art. 132900
- Mcloone, P.; Zhumbayeva, A.; Yunussova, S.; Kaliyev, Y.; Yevstafeva, L.; Sungurtas, J.; Verrall, S.; Austin, C.; Allwood, W.; McDougall, G.J. (2021) Identifcation of components in Kazakhstan honeys that correlate with antimicrobial activity against wound and skin infecting microorganisms, BMC Complementary Medicine and Therapies, 21, Art. 300
- Allwood, W.; Martinez-Martin, P.; Xu, Y.; Cowan, A.; Pont, S.; Griffiths, I.; Sungurtas, J.; Clarke, S.; Goodacre, R.; Marshall, A.; Stewart, D.; Howarth, C. (2021) Assessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches, Food Chemistry, 335, Art. 12958
- Allwood, W.; Williams, A.; Uthe, H.; Van Dam, N.M. ; Mur, L.A.J. ; Grant, M.R. ; Pétriacq, P.; (2021) Unravelling Plant Responses to Stress—The Importance of Targeted and Untargeted Metabolomics, Metabolites, 11(8), Art. 558
- Alkhalefah, A.; Dunn, W. B.; Allwood, W.; Parry, K. L.; Houghton, F. D ; Ashton, N.; Glazier, J .D. (2021) Maternal intermittent fasting during pregnancy induces fetal growth restriction and down-regulated placental system A amino acid transport in the rat, Clin Sci (Lond), 135(11), 1445 - 1466
- Biancacci, C.; McDougall, G.J.; Allwood, J.W.; Day, J.G.; Davidson, K.; Stanley, M.S. (2021) LC-MSn profiling reveals seasonal variation in the composition of Osmundea pinnatifida (Hudson) Stackhouse, Journal of Applied Phycology, 33, 2443-2458
- Lima, R.C.L.; Böcker, U.; McDougall, G.J.; Allwood, J.W.; Afseth, N.K.; Wubshet, S.G. (2021) Magnetic ligand fishing using immobolized DPP-IV for identification of antidiabetic ligands in lingonberry extract, PLoS ONE, 16(2), Article No. e0247329
- Dobani, S.; Latimer, C.; McDougall, G.J.; Allwood, J.W.; Pereira-Caro, G.; Moreno-Rojas, J.M.; Ternan, N.G.; Pourshahidi, L.K.; Lawther, R.; Tuohy, K.M.; Del Rio; D.; O’Connor, G.; Rowland, I.; Almutairi, M.T.; Crozier, A.; Gill, C.I.R. (2021) Ex vivo fecal fermentation of human ileal fluid collected after raspberry consumption modifies (poly)phenolics and modulates genoprotective effects in colonic epithelial cells., Redox Biology, 40, Article No. 101862
- Allwood, J.M.; Gibon, Y.; Osorio, S.; Araújo, W.L.; Vallarino, J.G.; Pétriacq, P.; Moing, A. (2021) Developmental metabolomics to decipher and improve fleshy fruit quality., Advances in Botanical Research, 98, 3-34
- Abukhabta, S,; Ghawi, S.K.; Karatzas, K.A.; Charalampopoulos, D.; McDougall, G.; Allwood, J.W.; Verrall, S.; Lavery, S.; Latimer, C.; Pourshahidi, K.; Lawther, R.; O’Connor, G.; Rowland, I.; Gil, C.I.R. (2021) Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforphane., European Journal of Nutrition, 60, 1263-1276
- Matos, M.S.; Anastácio, J.D.; Allwood, J.W.; Carregosa, D.; Marques, D.; Sungurtas, J.; McDougall, G.J.; Menezes, R.; Matias, A.A.; Stewart, D.; Nunes dos Santos, C. (2020) Assessing the intestinal permeability and anti-inflammatory potential of sesquiterpene lactones from chicory., Nutrients, 12, Article No. 3547.
- Allwood, J.W.; Evans, H.; Austin, C.; McDougall, G.J. (2020) Extraction, Enrichment, and LC-MSn-Based Characterization of Phlorotannins and Related Phenolics from the Brown Seaweed, Ascophyllum nodosum, Marine Drugs, 18, Article No. 448.
- Okamoto, H.; Ducreux, L.J.M.; Allwood, J.W.; Hedley, P.E.; Wright, A.; Gururajan, V.; Terry, M.J.; Taylor, M.A. (2020) Light regulation of chlorophyll and glycoalkaloid biosynthesis during tuber greening of potato S. tuberosum., Frontiers in Plant Science, 11, Article No. 753.
- Moing, A.; Allwood, J.W.; Aharoni, A.; Baker, J.; Beale, M.H.; Ben-Dor, S.; Biais, B.; Brigante, F.; Burger, Y.; Deborde, C.; Erban, A.; Faigenboim, A.; Gur, A.; Goodacre, R.; Hansen, T.H.; Jacob, D.; Katzir, N.; Kopka, J.; Lewinsohn, E.; Maucourt, M.; Meir, S.; Miller, S.; Mumm, R.; Oren, E.; Paris, H.S.; Rogachev, I.; Rolin, D.; Saar, U.; Schjoerring, J.K.; Tadmor, Y.; Tzuri, G.; de Vos, R.C.H.; Ward, J.L.; Yeselson, E.; Hall, R.D.; Schaffer, A.A. (2020) Comparative metabolomics and molecular phylogenetics of melon (Cucumis melo, Cucurbitaceae) biodiversity., Metabolites, 10, Article No.121.
- McDougall, G.J.; Foito, A.; Dobson, G.; Austin, C.; Sungartas, J.; Su, S.; Wang, L.; Feng, C.; Li, S.; Wang, L.; Wei, W.; Allwood, J.W.; Stewart, D. (2020) Glutathionyl-S-chlorogenic acid is present in fruit of Vaccinium species, potato tubers and apple juice., Food Chemistry, 330, Article No. 127227.
- Mori, K.; Beauvoit, B.P.; Benoît, B.; Maxime, C.; Allwood, J.W.; Deborde, C.; Maucourt, M.; Goodacre, R.; Cabasson, C.; Moing, A.; Rolin, D.; Gibon, Y. (2019) Central metabolism Is tuned to the availability of oxygen in developing melon fruit., Frontiers in Plant Science, 10, Article No.594.
- Hayward, N.J.; McDougall, G.J.; Farag, S.; Allwood, J.W.; Austin, C.; Campbell, F.; Horgan, G.; Ranawana, V. (2019) Cinnamon shows antidiabetic properties that are species-specific: effects on enzyme activity inhibition and starch digestion., Plant Foods for Human Nutrition, 74, 544-552.
- Haugeneder, A.; Trinkl, J.; Hartl, K.; Hoffmann, T.; Allwood, J.W.; Schwab, W. (2019) Correction to: answering biological questions by analysis of the strawberry metabolome (vol 14, 145, 2018)., Metabolomics, 15, p40.
- Kallscheuer, N.; Menezes, R.; Foito, A.; Silva, M.H.; Braga, A.; Dekker, W.; Sevillano, D.M.; Rosado-Ramos, R.; Jardim, C.; Oliveira, J.; Ferreira, P.; Rocha, I.; Silva, A.R.; Sousa, M.; Allwood, J.W.; Bott, M.; Faria, N.; Stewart, D.; Ottens, M.; Naesby, M.; Santos, C.N.; Marienhagen, J. (2019) Identification and microbial production of the raspberry phenol Salidroside that is active against Huntington’s Disease., Plant Physiology, 179, 969-985.
- Allwood, J.W.; Xu, Y.; Martinez-Martin, P.; Palau, R.; Cowan, A.; Goodacre, R.; Marshall, A.; Stewart, D.; Howarth, C. (2019) Rapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats., Metabolomics, 15, Article No. 42.
- Allwood, J.W.; Woznicki, T.L.; Xu, Y.; Foito, A.; Aaby, K.; Sungurtas, J.; Freitag, S.; Goodacre, R.; Stewart, D.; Rember, S.F.; Heide, O.M.; Sønsteby, A. (2019) Application of HPLC-PDA-MS metabolite profiling to investigate the effect of growth temperature and day length on blackcurrant fruit., Metabolomics, 15, Article No. 12.
- Solopova, A.; van Tilburg, A.Y.; Foito, A.; Allwood, J.W.; Stewart, D.; Kulakauskas, S.; Kuipers, O.P. (2019) Engineering Lactococcus lactis for the production of unusual anthocyanins using tea as substrate., Metabolic Engineering, 54, 160-169.
- Logie, L.; Lees, Z.; Allwood, J.W.; McDougall, G.J.; Beall, C.; Rena, G. (2018) Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)., Diabetes, Obesity and Metabolism, 20, 2748-2758.
- Freitag, S.; Verrall, S.R.; Pont, S.D.A.; McRae, D.; Sungartas, J.A.; Palau, R.; Hawes, C.; Alexander, C.J.; Allwood, J.W.; Foito, A.; Stewart, D.; Shepherd, L.V.T. (2018) Impact of conventional and integrated management systems on the water-soluble vitamin content in potatoes, field beans and cereals., Journal of Agricultural and Food Chemistry, 66, 831-841.
- Austin, C.; Stewart, D.; Allwood, J.W.; McDougall, G.J. (2018) Extracts from the edible seaweed, Ascophyllum nodosum, inhibit lipase activity in vitro: contributions of phenolic and polysaccharide components., Food and Function, 9, 502-510.
- Armitage, E.G.; Kotze, H.L.; Allwood, J.W.; Dunn, W.B.; Goodacre, R.; Williams, K.J. (2015) Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signaling in hypoxic cancer cells., Scientific Reports, 5, Article No. 15649.
- Allwood, J.W.; Alrabiah, H.; Correa, E.; Vaughan, A. Xu, Y.; Upton, M.; Goodacre, R. (2015) A workflow for bacterial metabolic fingerprinting and lipid profiling: application to Ciprofloxacin challenged Escherichia coli., Metabolomics, 11, 438-453.
- Armitage, E.G.; Kotze, H.L.; Allwood, J.W.; Dunn, W.B.; Goodacre, R.; Williams, K.J. (2015) Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells., Scientific Reports, 5, Article 15649.
- Gehmlich, K.; Dodd, M.; Allwood, J.W.; Kelly, M.; Bellahcene, M.; Lad, H.; Stockenhuber, A.; Hooper, C.; Ashrafian, H.; Redwood, C.; Carrier, L.; Dunn, W.B. (2015) Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy., Molecular BioSystems, 2, 564-573.
- Mullard, G.; Allwood, J.W.; Weber, R.; Brown, M.; Begley, P.; Hollywood, K.A.; Jones, M.; Unwin, R.D.; Bishop, P.N.; Cooper, G.J.S.; Dunn, W.B. (2015) A new strategy for MS/MS data acquisition applying multiple data dependent experiments on Orbitrap mass spectrometers in non-targeted metabolomic applications., Metabolomics, 11, 1068-1080.
- Muhamadali, H.; Xu, Y.; Ellis, D.I.; Allwood, J.W.; Rattray, N.J.W.; Correa, E.; Alrabiah, H.; Lloyd, J.R.; Goodacre, R. (2015) Metabolic profiling of Geobacter sulfurreducens during industrial bioprocess scale-up., Applied and Environmental Microbiology, 81, 3288-3298.
- Allwood, J.W.; Chandra, S.; Xu, Y.; Dunn, W.B.; Correa, E.; Hopkins, L.; Goodacre, R.; Tobin, A.K.; Bowsher, C.G. (2015) Profiling of spatial metabolite distributions in wheat leaves under normal and nitrate limiting conditions., Phytochemistry, 115, 99-111.
- Dyson, B.C.; Allwood, J.W.; Feil, R.; Xu, Y.; Miller, M.; Bowsher, C.G.; Goodacre, R.; Lunn, J.E.; Johnson, G.N. (2015) Acclimation of metabolism to light in Arabidopsis thaliana: the glucose 6-phosphate/phosphate translocator GPT2 directs metabolic acclimation., Plant, Cell and Environment, 38, 1404-1417.
- Kim, D.-H.; Allwood, J.W.; Moore, R.E.; Marsden-Edwards, E.; Dunn, W.B.; Xu, Y.; Hampson, L.; Hampson, I.N.; Goodacre, R. (2014) A metabolomics investigation into the effects of HIV protease inhibitors on HPV16 E6 expressing cervical carcinoma cells., Molecular Biosystems, 10, 398-411.
- Alrabiah, H.; Xu, Y.; Rattray, N.J.W.; Vaughan, A.; Gibreel, T.; Sayqal, A.; Upton, M.; Allwood, J.W.; Goodacre, R. (2014) Multiple metabolomics of uropathogenic E. coli reveal different information content in terms of metabolic potential compared to virulence factors., Analyst, 139, 4193-4199.
- Allwood, J.W.; Cheung, W.; Xu, Y.; Mumm, R.; De Vos, R.C.H.; Deborde, C.; Biais, B.; Maucourt, M.; Berger, Y.; Schaffer, A.A.; Rolin, D.; Moing, A.; Hall, R.D.; Goodacre, R. (2014) Metabolomics in melon: a new opportunity for aroma analysis., Phytochemistry, 99, 61-72.
- Hooks, M.A.; Allwood, J.W.; Harrison, J.K.D.; Kopka, J.; Erban, A.; Goodacre, R.; Balk, J. (2014) Selective induction and subcellular distribution of ACONITASE 3 reveal the importance of cytosolic citrate metabolism during lipid mobilization in Arabidopsis., Biochemical Journal, 463, 309-317.
- Bradbury, J.; Genta-Jouve, G.; Allwood, J.W.; Dunn, W.B.; Goodacre, R.; Knowles, J.D.; He, S.; Viant, M.R. (2014) MUSCLE: automated multi-objective evolutionary optimisation of LC-MS/MS analysis., Bioinformatics, 31, 975-977.
- Allwood, J.W.; Winder, C.L.; Dunn, W.B.; Goodacre, R. (2013) Considerations in sample preparation, collection and extraction approaches applied in microbial, plant and mammalian metabolic profiling., In: Lutz, N.W., Sweedler, J. & Wevers, R.A. (eds.). Methodologies for Metabolomics: Experimental Strategies and Techniques. Cambridge University Press, Chapter 4, pp79-118.
- Mabbott, S.; Correa, E.; Cowcher, D.P.; Allwood, J.W.; Goodacre, R. (2013) Optimisation of parameters for the quantitative surface-enhanced Raman scattering detection of mephedrone using a fractional factorial design and a portable Raman spectrometer., Analytical Chemistry, 85, 923-931.
- Allwood, J.W.; Weber, R.J.M.; Zhou, J.; He, S.; Viant, M.R.; Dunn, W.B. (2013) CASMI - The small molecule identification process from a Birmingham perspective., Metabolites, 3, 397-411.
- Kotze, H.L.; Armitage, E.G.; Sharkey, K.J.; Allwood, J.W.; Dunn, W.B.; Williams, K.J.; Goodacre, R. (2013) A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions., BMC Systems Biology, 7, Article No. 107.
- Zhou, J.; Weber, R.J.M.; Allwood, J.W.; Mistrik, R.; Zhu, Z.; Ji, Z.; Chen, S.; Dunn, W.B.; He, S.; Viant, M.R. (2013) HAMMER: Automated operation of mass frontier to construct in-silico mass spectral fragmentation libraries., Bioinformatics, 30, 581-583.
- Allwood, J.W.; Heald, J.; Lloyd, A.J.; Goodacre, R.; Mur, L.A.J. (2012) Separating the inseparable: The metabolomic analysis of plant-pathogen interactions., In: Hardy, N. & Hall, R. (eds.) Plant Metabolomics. Methods in Molecular Biology (Methods and Protocols). Humana Press, Volume 860, pp31-49..
- Allwood, J.W.; Parker, D.; Beckmann, M.; Draper, J.; Goodacre, R. (2012) Fourier transform ion cyclotron resonance mass spectrometry for plant metabolite profiling and metabolite identification., In: Hardy, N. & Hall, R. (eds.) Plant Metabolomics. Methods in Molecular Biology (Methods and Protocols). Humana Press, Volume 860, pp157-176.
- Ellis, D.I.; Brewster, V.L.; Dunn, W.B.; Allwood, J.W.; Golovanov, A.P.; Goodacre, R. (2012) Fingerprinting food: current technologies for the detection of food adulteration and contamination., Chemical Society Reviews, 41, 5706-5727.
- Vaughan, A.A.; Dunn, W.B.; Allwood, J.W.; Wedge, D.C.; Blackhall, F.H.; Whetton, A.D.; Dive, C.; Goodacre, R. (2012) Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion., Analytical Chemistry, 84, 9848-9857.
- Kopka, J.; Walther, D.; Allwood, J.W.; Goodacre, R. (2011) Progress in chemometrics and biostatistics for plant applications, or: a good red wine is a bad white wine., In: Hall, R.D. (ed.). Biology of Plant Metabolomics. Blackwell, Oxford UK, Chapter 10, pp317-342.
- Allwood, J.W.; De Vos, R.C.H.; Moing, A.; Deborde, C.; Erban, A.; Kopka, J.; Goodacre, R.; Hall, R.D. (2011) Plant metabolomics and its potential for systems biology research: background concepts, technology and methodology., In: Jameson, D., Verma, M. & Westerhoff, H.V. (eds.). Methods in Enzymology: Methods in Systems Biology. Elsevier Science, 500, 299-336.
- Moing, A.; Aharoni, A.; Biais, B.; Rogachev, I.; Meir, S.; Brodsky, L.; Allwood, J.W.; Erban, A.; Dunn, W.B.; Kay, L.; de Koning, S.; de Vos, C.H.R.; Jonker, H.; Mumm, R.; Deborde, C.; Maucourt, M.; Bernillon, S.; Gibon, Y.; Hansen, T.H.; Husted, S.; Goodacre, R.; Kopka, J.; Schjoerring, J.K.; Rolin, D.; Hall, R.D. (2011) Extensive metabolic cross-talk in melon fruit revealed by spatial and developmental combinatorial metabolomics., New Phytologist, 190, 683-696.
- Wedge, D.C.; Allwood, J.W.; Dunn, W.B.; Vaughan, A.A.; Simpson, K.; Brown, M.; Priest, L.; Blackhall, F.H.; Whetton, A.D.; Dive, C.; Goodacre, R. (2011) Is serum or plasma more appropriate for inter-subject comparisons in metabolomic studies? An assessment in patients with small-cell lung cancer., Analytical Chemistry, 83, 6689-6697.
- Lloyd, A.J.; Allwood, J.W.; Winder, C.L.; Dunn, W.B.; Heald, J.K.; Cristescu, S.M.; Sivakumaran, A.; Harren, J.F.M.; Mulema, J.; Denby, K.; Goodacre, R.; Smith, A.R.; Mur, L.A.J. (2011) Metabolomic approaches reveal that cell wall modifications play a major role in ethylene-mediated resistance against Botrytis cinerea., Plant Journal, 67, 852-868.
- Biais, B.; Beauvoit, B.; Allwood, J.W.; Deborde, C.; Maucort, M.; Goodacre, R.; Rolin, D.; Moing, A. (2010) Metabolic acclimation to hypoxia revealed by metabolite gradients in melon fruit., Journal of Plant Physiology, 167, 242-245.
- Kim, D.-H.; Jarvis, R.M.; Xu, Y.; Oliver, A.W.; Allwood, J.W.; Hampson, L.; Hampson, I.N.; Goodacre, R. (2010) Combining metabolic fingerprinting and footprinting to understand the phenotypic response of HPV16 E6 expressing cervical carcinoma cells exposed to the HIV anti-viral drug lopinavir., Analyst, 135, 1235-1244.
- Kim, D.-H.; Jarvis, R.M.; Allwood, J.W.; Batman, G.; Moore, R.E.; Marsden-Edwards, E.; Hampson, L.; Hampson, I.N.; Goodacre, R. (2010) Raman chemical mapping reveals site of action of HIV protease inhibitors in HPV16 E6 expressing cervical carcinoma cells., Analytical and Bioanalytical Chemistry, 398, 3051-3061.
- Roberto, B.; Martins, I.; Stewart, D.; Allwood, W.; McDougall, G.J.; Macedo, G. (2017) The effects of bio-transformed green and white teas on alpha-amylase activity., Proceedings of the International Conference on Polyphenols and Health, Quebec, Canada, 3-6 October 2017, Book of Abstracts, p216.
- Allwood, W.; Austin, C.; Wright, S.; Plummer, C.; McDougall, G. (2022) Characterisation of phlorotannins and other phenolic components from brown seaweeds, International Conference on Polyphenols and Health, 20-23 April 2022, London
- Allwood, J.W.; Woznicki, T.L.; Xu, Y.; Foito, A.; Aaby, K.; Sungurtas, J.; Freitag, S.; Goodacre, R.; Stewart, D.; Remberg, S.F.; Heide, O.M.; Sønsteby, A. (2020) Application of HPLC-PDA-MS metabolite profiling to investigate the effect of growth temperature and day length on blackcurrant fruit., RFMF-MPF MetaboMeeting 2020, University of Toulouse, 22-24 January 2020. Poster.
- McDougall, G.J.; Allwood, J.W.; Dobson, G.; Stewart, D.; Crozier, A.; Gill, C.I.R. (2018) Novel bioactive triterpenoids in Rubus: Variation due to tissue, extraction and genotype., 2nd International Conference on Food Bioactives and Health, Lisbon, Portugal, 26-28 September 2018. (Poster)
- Allwood, J.W.; Xu, Y.; Palau, R.; Shepherd, T.; Howarth, C.; Martinez Martin, P.; Marshall, A.; Clarke, S.; Goodacre, R.; Stewart, D. (2017) Application of metabolomics approaches to study the effect of nitrogen elevation on winter oat metabolite composition and quality traits., Scottish Metabolomics Network 3rd Annual Symposium, City of Glasgow College, Glasgow, 2-3 November 2017. Poster 6.
- Austin, C.; Stewart, D.; Allwood, J.W.; McDougall, G.J. (2017) Edible seaweeds inhibit pancreatic lipase in vitro., International Conference on Natural Product Biotechnology, AECC, Aberdeen, 25-26 September 2017. Book of Abstracts, p24. (Poster)
- Dobson, G.; Shepherd, T.; Allwood, W.; Palau, R.; McRae, D.; Pont, S.; Sungurtas, J.; Alexander, C.; Verrall, S.; Stewart, D.; Shepherd, L. (2017) Comparison of rapeseed grown sustainably and conventionally. A comparison of the quality of oil and meal from winter oilseed rape grown under sustainable and conventional practices., International Conference on Natural Product Biotechnology, AECC, Aberdeen, 25-26 September 2017.
- Munir, H.; Benjamin, A.; Allwood, J.W.; Dunn, W.B.; He, S.; Nash, G.B.; McGettrick, H.M. (2016) A1.18 Mesenchymal stem cells lose their immuno-protective effects upon changes in their local microenvironment., 36th European Workshop for Rheumatology Research, York, UK, 25-27 February 2016. Special Issue of Annals of the Rheumatic Diseases, 75, A8.
- Mackie, F.L.; Dunn, W.B.; Allwood, J.W.; Van Mieghem, T.; Morris, R.K.; Fox, C.E.; Kilby, M.D. (2016) OC09.03: Metabolomic changes in amniotic fluid from Twin-twin transfusion syndrome recipient twins in relation to treatment and fetal cardiovascular risk., 26th World Congress on Ultrasound in Obstetrics and Gynecology, Rome, Italy, 25-28 September 2016. Special issue of Ultrasound in Obstetrics and Gynecology, 48, 16-17. Oral communication and Abstract OC09.03.
